The prognostic value of serum levels of a proliferation-inducing ligand (APRIL) in treatment-naïve patients with chronic lymphocytic leukemia
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15 صفحه اولAPRIL but not BLyS serum levels are increased in chronic lymphocytic leukemia: prognostic relevance of APRIL for survival.
APRIL (a proliferation-inducing ligand) and BLyS (B lymphocyte stimulator) expression have been reported in chronic lymphocytic leukemia (CLL) cells. We examined APRIL and BLyS serum levels in CLL patients and evaluated the prognostic significance of APRIL expression on survival.
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BACKGROUND B cells have been demonstrated to have critical roles in developing autoimmune bullous diseases. Recently identified tumor necrosis factor-like molecules, B cell-activating factor of the TNF family (BAFF) and a proliferation-inducing ligand (APRIL) are essential molecules for B cell development, survival, and proliferation. Although the functions of APRIL have not been fully evaluate...
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E, Biondi F, Lo Coco F, Grignani F, Pelicci PG: Acute promyelocytic REFERENCES leukemia: From genetics to treatment. Blood 83:10, 1994 1. Wada H, Mizutani S, Nishimura J, Usuki Y, Kohsaki M, Komai 5. Nucifora G, Rowley JD: The AML1 and ETO genes in acute M, Kaneko H, Sakamoto S, Delia D, Kanamaru A, Kakishita E: myeloid leukemia with a t(8;21). Leuk Lymphoma 14:353, 1994 Establishment and molec...
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ژورنال
عنوان ژورنال: TURKISH JOURNAL OF MEDICAL SCIENCES
سال: 2021
ISSN: 1303-6165
DOI: 10.3906/sag-2004-282